History: New York Giants vs. San Francisco 49ers
- All Time Record: The Giants are 17-16 against the 49ers in the regular season.
- Interesting Facts: The teams have met 41 times combined in the regular season and postseason. The Giants have 21 victories, the 49ers have 20. In those 41 games, they are separated by only five points (Giants 843, 49ers 838).
- Streaks: n/a
- 2018 Results: Giants defeated the 49ers 27-23 on November 12, 2018.
Players and Coaches to Know
San Francisco 49ers
- Head Coach Kyle Shanahan
- Quarterback Jimmy Garoppolo
- Position Player Name George Kittle, Nick Bosa
New York Giants
- Head Coach Joe Judge
- Quarterback Name Daniel Jones
- Position Player Name Saquon Barkley, Leonard Williams