Last week: W, 31-24, vs. Philadelphia EaglesRecord: 4-1 (1-1 away)Streak: W-1The good: The Bills have already matched last season's win total and are off to their best start since 2008, scoring more than 30 points in four of their first five games. Buffalo's four interceptions against Michael Vick was the second time the Bills had four picks in a game (the other was against the New England Patriots). The Bills' 12 interceptions and their +11 turnover ratio are both league bests. The bad: Bills rank 30th in pass defense (283.4 yds/g) and are 29th against the run (138.4). In their only loss (at Cincinnati, 23-20), the Bills gave up 458 total yards to their 273.Under center: Ryan Fitzpatrick, 6-2, 225, St. Louis Rams' 7th round draft pick in 2005 out of Harvard. 2011 stats: 113 of 172 passing (65.7%), 1233 yards, 10 TD, 4 INT.Ground: Fred Jackson, 6-1, 215, Undrafted in 2003 out of Coe College. Tied for 1st in NFL with seven runs of 20+ yards, averages 99.6 yds/g (4th), six rushing TDs (T-2nd).Wide out: Steve Johnson, 6-2, 210, Bills; 7th round draft pick out of Kentucky. 2011 stats: 28 rec., 343 yards, 3 TD.Defense: Safety George Wilson is the AFC Defensive Player of the Week after posting nine tackles, three pass breakups and an interception against the Eagles.Injury report: Wide receiver Donald Jones, Buffalo's deep threat, is out 4-6 weeks with a high-ankle sprain suffered last week. Non-participants at Wednesday's practice: DB Aaron Williams (chest), DB Da'Norris Searcy (ankle), LB Shawne Merriman (shoulder), OL Andy Levitre (knee), OL Demetrius Bell (shoulder), LB Chris Kelsay (calf), NT Kyle Williams (foot).