This week's game is the 30th regular season meeting between the two teams. The Giants lead the series 15-14. The teams have met eight times in the postseason, where the series is, 4-4.
The game will be broadcast on Fox. Fans in the tri-state area can also listen to the game on the radio at WFAN 660 AM/101.9 FM courtesy of the Giants Radio Network. The Giants Spanish Radio Broadcast, Giants en Español, can be heard on WADO 1280AM.
Giants.com & and the Giants Mobile App will also stream the radio feed of the game. You can downloaded the app for free.
**>> Radio affiliates** | **5 players to watch vs. 49ers**
PREGAME INFORMATION
Coors Light Gameday at 11:30 AM ET and can be heard on WFAN 660 AM/101.9 FM. Giants.com & the Giants Mobile App will also stream the pregame show live.
POSTGAME INFORMATION
Immediatly following the game, fans in the tri-state area can watch Postgame Live on MY9 and streamed live on Giants.com/Giants Mobile App.
Russ Salzberg, Roman Oben, Shaun O'Hara, Howard Cross and Amani Toomer host 'Giants Post Game Live' immediately following every game on WWOR-TV MY9. Fans tuning in can watch Tom Coughlin's and Eli Manning's postgame press conferences live, as well as live, exclusive interviews with the games stars and players with Paul Dottino inside the locker room. The game is broken down and analyzed using stats, highlights and telestration. Live fan Twitter comments are updated throughout the show.
Keep an eye on these 5 players as the Giants face the 49ers on Sunday

RB Rashad Jennings Jennings is listed as probable to make his return on Sunday after missing the past four games with a knee injury. In five games this season, Jennings has 91 rushing attempts for 396 yards and two touchdowns, in addition to 11 catches for 109 yards. "Anxious is a good word, anxious to get back on the field," Jennings said. "This is my livelihood, this is what I do as a profession. It's my job, it's my business, it's what I love to do. When you're unable to perform on the field, you feel like something's stripped away from you, but it was a time where I think on and off the field I was able to recalibrate some things and come back to the game with a stronger perspective.">> TEAM ANTICIPATES OFFENSIVE BOOST WITH JENNINGS' RETURN

LB Devon Kennard In addition to Mark Herzlich and Spencer Paysinger, the rookie Kennard will be used in the linebacker rotation to compensate for Jacquian Williams, who is out with a concussion. After allowing 350 rushing yards to quarterback Russell Wilson and the Seattle Seahawks last week, the Giants' entire front seven will have to be on their game against a similar threat in Colin Kaepernick and the San Francisco 49ers. "I feel comfortable," Kennard said. "I am excited for the opportunity and it is something I have been working towards all camp and everything and all this season so far. I feel ready for the opportunity."

WR Odell Beckham Jr. A bright spot in the Giants' current four-game losing streak has been the emergence of Beckham, the team's rookie first-round draft pick. Beckham is leading the league in receiving yards over the last two weeks, including 108 against Seattle's vaunted secondary. "That's another one of those things where it's great, but without winning, it's just kind of like, 'OK,'" Beckham said. "That's just one of those things that I just want to keep continuing to improve and do more, do more for the team.">> THE BECKHAM JR. REPORT: EXCLUSIVE GIANTS.COM INTERVIEW

S Stevie Brown After Quintin Demps replaced him as a starter in Week 4, Brown has seen his number of snaps gradually increase back up over the last few weeks and could be a factor in more three-safety looks. "We're trying to get both guys integrated," defensive coordinator Perry Fewell said. "We'll try to use a little bit of the three-safety package a little bit. Nothing out of the ordinary."

DE Robert Ayers Jr. Ayers has registered a sack in back-to-back games, bringing his season total to a team-high four. However, in spite of Ayers' efforts, the defense has dropped to last in the NFL in yards allowed per game. Now Ayers and the Giants will try to crawl out. "We're at the 32nd spot right now," Fewell said. "We have seven games to crawl out of that spot. We'll crawl out."