Defensive lineman Leonard Williams suffered a knee injury midway through the third quarter of Sunday's game against the Panthers and did not return.
The defensive co-captain has missed just one game in his entire eight-year career.
Stay tuned to Giants.com for more information.
View photos from the Giants' Week 2 game vs. the Carolina Panthers at MetLife Stadium.
Carolina Panthers' Jeremy Chinn, left, tries unsuccessfully to stop New York Giants' Daniel Bellinger from scoring a touchdown during the second half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones looks to throw during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones (8) calls a play during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' Kadarius Toney, right, runs with the ball during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants' Tanner Hudson, right, runs with the ball during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants place kicker Graham Gano (9) kicks a field goal during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones runs with the ball during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones runs with the ball during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' David Sills V runs with the ball during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants quarterback Daniel Jones runs with the ball during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' David Sills V, right, fends off Carolina Panthers' Xavier Woods during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
Carolina Panthers' Chuba Hubbard, right, fumbles the ball during the first half an NFL football game against the New York Giants, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants' Saquon Barkley, left, runs the ball during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones, top right, calls a play during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' Adoree' Jackson (22), top, breaks up a pass intended for Carolina Panthers' DJ Moore (2) during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones throws during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants' Julian Love, right, tries to tackle Carolina Panthers quarterback Baker Mayfield during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones throws during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants' Julian Love, right, tries to tackle Carolina Panthers quarterback Baker Mayfield during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants running back Saquon Barkley, left, tries to break tackles during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants' Julian Love, left, tackles Carolina Panthers' Christian McCaffrey during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants' Leonard Williams (99) reacts during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' Dane Belton, right, tackles Carolina Panthers' Ian Thomas during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants quarterback Daniel Jones looks to throw during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
New York Giants' Darnay Holmes during the first half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants quarterback Daniel Jones throws during the first half an NFL football game Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' Kadarius Toney, right, tries to avoid a tackle by Carolina Panthers' Myles Hartsfield during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' Daniel Bellinger, right, celebrates his touchdown with Richie James during the second half an NFL football game against the Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' Daniel Bellinger during the second half an NFL football game Carolina Panthers, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
Carolina Panthers' Jeremy Chinn, top, tries unsuccessfully to stop New York Giants' Daniel Bellinger from scoring a touchdown during the second half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/John Munson)
New York Giants' Daniel Bellinger, bottom, scores a touchdown past Carolina Panthers' Jeremy Chinn during the second half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Noah K. Murray)
