The New York Giants open the 2022 season with a trip to Nashville, Tenn. to take on the Tennessee Titans. Kickoff in Nissan Stadium is set for 4:25 p.m. ET on Fox.
Sunday marks the beginning of the Brian Daboll era for the Giants, the 20th head coach in franchise history. Daboll's first game as an NFL head coach comes against a familiar opponent in Tennessee Head Coach Mike Vrabel. The two overlapped in New England from 2001-06 with Daboll serving as a defensive assistant (2001) and wide receivers coach (2002-06) and Vrabel playing linebacker.
The all-time series is tied at 6-6 between the two clubs. The Giants have a 3-3 record on the road against the Titans.
Channel: FOX (4:25 p.m. ET Kickoff)
Announcers: Kevin Kugler (Play-by-Play), Mark Sanchez (Analyst), Laura Okim (Sideline)
Postgame: Madelyn Burke, Shaun O'Hara, and Victor Cruz on Giants Postgame Live
"Giants Postgame Live" is the official one-hour postgame show that will air live immediately following the game on MSG Network and stream live on Giants.com, the Giants mobile app, "Giants TV" streaming app, and the Giants' YouTube Channel.
WATCH ON MOBILE
Live stream this week's game on NFL+
*Geographic and device restrictions apply. Local & Primetime games only. Data charges may apply.
LISTEN LIVE
Channel: WFAN 660AM
Play-by-Play: Bob Papa
Analyst: Carl Banks
Sideline: Howard Cross
Pregame: Lance Medow, Jeff Feagles, Paul Dottino, John Schmeelk
Postgame: Bob Papa, Carl Banks, Lance Medow, Jeff Feagles, John Schmeelk
Giants Gameday radio pregame show, presented by Bud Light, will begin at 2:10 p.m. on WFAN 660AM. Giants Postgame Live presented by Pepsi can be heard immediately after the game - also on WFAN 660AM.
GIANTS EN ESPAÑOL
Channel: X96.3 FM Univision
Play-by-Play: Nestor Rosario
Analyst: Francis Adames
NATIONAL RADIO
Channel: SiriusXM NFL
HIGHLIGHTS FROM THE GAME
Find all of the big plays and important action from this clash on:
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SOCIAL MEDIA ACCOUNTS
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View rare photos of the all-time history between the New York Giants and Tennessee Titans.
Quarterback Archie Manning of the Houston Oilers loses the ball as he is sacked by George Martin of the New York Giants in the final minutes of their game at Giants Stadium in East Rutherford, N.J., Dec. 5, 1982.
Houston Oilers quarterback Warren Moon is sacked for a five yard loss by New York Giants Leonard Marshall, left, and Corey Miller in the second quarter at Giants Stadium on Saturday, Dec. 21, 1991 in East Rutherford, New Jersey. The Giants won 24-20. (AP Photo/Mark Phillips)
New York Giants quarterback Phil Simms (11) takes a snap during the NFL football game against the Houston Oilers on Dec. 21, 1991 in East Rutherford, N.J. The Giants won the game 24-20. (Paul Spinelli via AP)
New York Giants wide receiver Mark Ingram (82) runs upfield during a 20 to 24 Houston Oilers loss to the New York Giants on December 21, 1991 at Giants Stadium in East Rutherford, New Jersey. (AP Photo/Paul Spinelli)
New York Giants wide receiver Amani Toomer (81) catches a pass as he is defended by Tennessee Titans cornerback Dainon Sidney (37) in the fourth quarter on Sunday, Oct. 1, 2000 in Nashville, Tenn. Toomer gained 40 yards on the play. The Titans won 28-14. (AP Photo/Wade Payne)
Keith Hamilton #75 of the New York Giants fights off a block during an NFL football game against the Tennessee Titans on September 30, 2000 in Nashville. The Titans won 28-14. (AP Photo/G. Newman Lowrance)
Jesse Armstead #98 of the New York Giants pursues on a play against the Tennessee Titans during an NFL football game on September 30, 2000 in Nashville. The Titans won 28-14. (AP Photo/G. Newman Lowrance)
New York Giants running back Tiki Barber (21) is hit by Tennessee Titans safety Perry Phenix (35) after Barber caught a pass for a 6-yard gain in the first quarter on Sunday, Oct. 1, 2000 in Nashville, Tenn. At left is line judge Mike Spanier. (AP Photo/Mark Humphrey)
Tennessee Titans quarterback Steve McNair (9) is dropped for a 4-yard loss as he is sacked by New York Giants defensive tackle Keith Hamilton (75) in the third quarter on Sunday, Oct. 1, 2000 in Nashville, Tenn. Also defending for the Giants are Cedric Jones (94) and Ryan Phillips (91). (AP Photo/John Russell)
New York Giants Michael Strahan during an NFL football game against the Tennessee Titans in East Rutherford,NJ at Giants Stadium Sunday, Dec.1, 2002. (AP Photo/Tom DiPace)
Tennessee Titans running back Eddie George (27) looks for running room as New York Giants linebacker Brandon Short (53) and defensive tackle Lance Legree (70) pursue during the first quarter Sunday, Dec. 1, 2002, at Giants Stadium in East Rutherford, N.J. George gained 64 yards on 20 attempts and scored a touchdown as the Titans beat the Giants 32-29 in overtime. (AP Photo/Bill Kostroun)
New York Giants Michael Strahan during an NFL football game against the Tennessee Titans in East Rutherford,NJ at Giants Stadium Sunday, Dec.1, 2002. (AP Photo/Tom DiPace)
New York Giants wide receiver Steve Smith (12) makes a catch and looks to fend off cornerback Cortland Finnegan (31) of the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
A look down the line of scrimmage as the New York Giants play against the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants' Antrel Rolle (26) talks with teammate Kenny Phillips (21)during the first quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Bill Kostroun)
New York Giants defensive lineman Chris Canty (99) tries to block a field goal attempt by the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants running backs Brandon Jacobs (27) celebrate Ahmad Bradshaws (44) 2nd quarter touchdown against the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants quaterback Eli Manning (10) points out the coverage against the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants wide receiver Mario Manningham (82) makes a catch against the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants quarterback Eli Manning (10) throws a pass during the fourth quarter of an NFL football game between the New York Giants and the Tennessee Titans Sunday, Sept. 26, 2010 in East Rutherford, N.J. The Titans won the game 29-10. (AP Photo/Bill Kostroun)
New York Giants wide receiver Hakeem Nicks (88) catches a pass as Tennessee Titans cornerback Cortland Finnegan (31) defends during the fourth quarter of an NFL football game between the New York Giants and the Tennessee Titans Sunday, Sept. 26, 2010 in East Rutherford, N.J. The Titans won the game 29-10. (AP Photo/Bill Kostroun)
The Tennessee Titans, left, line up against the New York Giants during the third quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010, in East Rutherford, N.J. (AP Photo/Seth Wenig)
Tennessee Titans linebacker Jamie Winborn, left, tries to stop New York Giants tight end Kevin Boss during the first quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants quarterback Eli Manning yells during the first quarter of an NFL football game against the Tennessee Titans at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
Tennessee Titans linebacker Jamie Winborn, left, tries to stop New York Giants tight end Kevin Boss during the first quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants tight end Kevin Boss runs the ball during the first quarter of an NFL football game against the Tennessee Titans at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants running back Ahmad Bradshaw runs during the first quarter of an NFL football game against the Tennessee Titans at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
Tennessee Titans quarterback Vince Young, left, during the first quarter of an NFL football game against the New York Giants at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants running back Ahmad Bradshaw (44) tries to get through Tennessee Titans defense during the first quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants quarterback Eli Manning yells during the first quarter of an NFL football game against the Tennessee Titans at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants defensive end Mathias Kiwanuka, left, reacts during the first quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Bill Kostroun)
New York Giants running back Ahmad Bradshaw (44) reacts to scoring a touchdown during the second quarter of an NFL football game against the Tennessee Titans at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants running back Ahmad Bradshaw (44) reacts to scoring a touchdown during the second quarter of an NFL football game against the Tennessee Titans at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants tight end Kevin Boss (89) breaks a tackle from Tennessee Titans' Jamie Winborn (52), below, as Titans' Jason McCourty (30) pursues during the first quarter of an NFL football game at New Meadowlands Stadium, Sunday, Sept. 26, 2010, in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants running back Ahmad Bradshaw (44) evades a tackle by Tennessee Titans' Michael Griffin (33) during the first quarter of an NFL football game at New Meadowlands Stadium on Sunday, Sept. 26, 2010, in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants quaterback Eli Manning (10) throws a pass against the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants running back Ahmad Bradshaw (44) is tackled by Tennessee Titans' Will Witherspoon (92) during the first quarter of an NFL football game at New Meadowlands Stadium, Sunday, Sept. 26, 2010, in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants head coach Tom Coughlin shakes hands with Tennessee Titans head coach Jeff Fisher after a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants quarterback Eli Manning (10) looks to pass during the first quarter of an NFL football game against the Tennessee Titans at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants running back Ahmad Bradshaw (44) is tackled by Tennessee Titans Will Witherspoon (92) during the first quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants running back Ahmad Bradshaw (44) is tackled by Tennessee Titans Will Witherspoon (92) during the first quarter of an NFL football game at New Meadowlands Stadium Sunday, Sept. 26, 2010 in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants defensive end Mathias Kiwanuka (94) reacts after sacking Tennessee Titans quarterback Vince Young during the first quarter of an NFL football game as Titans' Jake Scott (73) looks on at New Meadowlands Stadium, Sunday, Sept. 26, 2010, in East Rutherford, N.J. (AP Photo/Seth Wenig)
New York Giants defensive end Justin Tuck (91) gives a pass rush against the Tennessee Titans in a week 3 NFL football game at the New Meadowlands Stadium in East Rutherford, New Jersey on Sunday September 26, 2010 (AP Photo/Evan Pinkus)
New York Giants running back Andre Williams (44) scores a touchdown against the Tennessee Titans on a 50-yard run in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. At left is Tennessee Titans linebacker Wesley Woodyard (59). (AP Photo/Mark Zaleski)
New York Giants quarterback Eli Manning (10) passes the football during a Week 14 NFL football game against the Tennessee Titans in Nashville, Tennessee on Sunday, December 7, 2014. The Giants defeated the Titans 36-7. (AP Photo/Scott Boehm)
New York Giants wide receiver Odell Beckham Jr. (13) tries to get past Tennessee Titans cornerback Jason McCourty (30) in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants strong safety Antrel Rolle (26) breaks up a pass intended for Tennessee Titans tight end Delanie Walker (82) during a week 14 football game against the on December 7, 2014 in Nashville, Tennessee (AP Photo/Evan Pinkus)
New York Giants quarterback Eli Manning (10) passes against the Tennessee Titans in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants running back Andre Williams (44) carries the ball during a week 14 football game against the Tennessee Titans on December 7, 2014 in Nashville, Tennessee (AP Photo/Evan Pinkus)
New York Giants quarterback Eli Manning (10) passes as Tennessee Titans defensive end Jurrell Casey (99) rushes in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants wide receiver Rueben Randle (82) runs against the Tennessee Titans in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants wide receiver Rueben Randle (82) leaps past Tennessee Titans safety George Wilson (21) in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants tight end Larry Donnell (84) gets past Tennessee Titans defensive back Marqueston Huff (28) in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
Tennessee Titans quarterback Zach Mettenberger (7) passes as he is hit by New York Giants defensive tackle Johnathan Hankins (95) in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants wide receiver Odell Beckham Jr. (13) catches a 15-yard touchdown pass ahead of Tennessee Titans cornerback Jason McCourty (30) in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants quarterback Eli Manning (10) passes as Tennessee Titans nose tackle Sammie Lee Hill (94) rushes in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
Tennessee Titans quarterback Jake Locker (10) is sacked by New York Giants defensive back Mike Harris (37) for a 10-yard loss in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. The Giants won 36-7. (AP Photo/James Kenney)
New York Giants middle linebacker Jameel McClain (53) sacks Tennessee Titans quarterback Zach Mettenberger (7) during a week 14 football game on December 7, 2014 in Nashville, Tennessee (AP Photo/Evan Pinkus)
New York Giants cornerback Dominique Rodgers-Cromartie (21) intercepts a pass during a week 14 football game against the Tennessee Titans on December 7, 2014 in Nashville, Tennessee (AP Photo/Evan Pinkus)
New York Giants tight end Larry Donnell (84) is dragged down by Tennessee Titans safety Michael Griffin (33) in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
Tennessee Titans quarterback Zach Mettenberger (7) is sacked by New York Giants outside linebacker Devon Kennard (59) in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. Mettenberger was injured on the play and left the game. (AP Photo/James Kenney)
New York Giants running back Tiki Barber (21) is brought down by Tennessee Titans safety Lamont Thompson, center, and linebacker Stephen Tulloch (55) in the first quarter of an NFL football game in Nashville, Tenn., Sunday, Nov. 26, 2006. (AP Photo/Mark Humphrey)
Tennessee Titans defensive back Brandon Harris (32) pushes New York Giants wide receiver Preston Parker (83) out of bounds in the first half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/Mark Zaleski)
New York Giants quarterback Eli Manning (10) calls a play against the Tennessee Titans in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. (AP Photo/James Kenney)
New York Giants running back Andre Williams (44) scores a touchdown against the Tennessee Titans on a 50-yard run in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. At left is Tennessee Titans safety George Wilson (21). (AP Photo/Mark Zaleski)
New York Giants running back Tiki Barber (21) protects the ball from Tennessee Titans safety Chris Hope (24) in the third quarter of an NFL football game in Nashville, Tenn., Sunday, Nov. 26, 2006. (AP Photo/John Russell)
New York Giants free safety Quintin Demps (35) intercepts a pass intended for Tennessee Titans tight end Delanie Walker, left, in the second half of an NFL football game Sunday, Dec. 7, 2014, in Nashville, Tenn. The Giants won 36-7. (AP Photo/Mark Zaleski)
