WR ODELL BECKHAM JR.

With a new contract extension in place, the three-time Pro Bowler is set to play in his first game in 336 days after suffering a season-ending ankle injury last October.

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RB SAQUON BARKLEY

The Jaguars leaned on Leonard Fournette throughout a deep playoff run last season, and now the Giants will try to do the same with another top-five rookie running back in Saquon Barkley.

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DT DAMON HARRISON

Jacksonville led the NFL in rushing last season, so what did the team do over the offseason? It added All-Pro guard Andrew Norwell. Harrison, one of the best run-stuffers in the game, will lead the defensive charge against the run-heavy Jaguars.

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LB ALEC OGLETREE

Giants defensive coordinator James Bettcher warned of the Jaguars' screen game in preparation for Sunday. Quarterback Blake Bortles is also known to tuck it and run. Both sound like jobs for a sideline-to-sideline player like Ogletree, one of six team captains.

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LT NATE SOLDER

The Giants have new starters at all five positions on the offensive line, including two-time Super Bowl champion Nate Solder. The former Patriot is charged with protecting Eli Manning's blindside, beginning with a Jacksonville defense that averaged 3.4 sacks per game in 2017.

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