1) Going, going, gone. The Giants failed to capitalize on David Wilson's 58-yard kick return to start the game, but there would be plenty more to come. Following Eli Manning's first-quarter interception that was returned for a touchdown, the rookie Wilson brought back the ensuing kickoff 97 yards for the equalizer. Those who follow the Giants knew it was only a matter of time, while it began a record-setting night for the franchise's first-round draft choice.
2) Collins fumbles, Joseph rumbles. Having already recovered a fumble on the Saints' previous drive, safety Antrel Rolle forced another midway through the first quarter. This time it was fullback Jed Collins coughing up the football, which defensive tackle Linval Joseph recovered and returned 16 yards down the sideline. The turnover led to Manning's six-yard touchdown strike to Martellus Bennett for a 14-7 lead.
3) Hixon's first touchdown. The Giants have excelled all season at putting up points just before halftime, and Sunday against the Saints was no different. With a one-point lead and 1:57 on the clock, Manning put together a nine-play, 69-yard drive that was capped by a five-yard fade to wide receiver Domenik Hixon in the back right corner of the end zone. It was Hixon's first touchdown of the year and first since suffering a season-ending knee injury in Week 2 of 2011.
4) Sproles turns the tables. Any comfort level the Giants felt with a 35-13 lead midway through the third quarter was quickly erased by Darren Sproles. Set up by a 62-yard completion from Drew Brees to Joseph Morgan, the New Orleans running back cut it to a two-possession deficit on a 13-yard touchdown run. The Saints defense then forced a three-and-out, which led to another Sproles touchdown – a nine-yard pass from Brees – to bring the score to 35-27 heading into the fourth quarter.
5) Brown notches second interception. Victor Cruz's touchdown on the second play of the fourth quarter stalled the Saints' hopes for a comeback, but Stevie Brown's interception (and 70-yard return) completely derailed that idea. Intended for Jimmy Graham, it was Brown's second interception of the game and seventh of the season. Brees was 4-0 against the Giants with 11 touchdowns and zero interceptions heading into the game. The turnover led a Lawrence Tynes field goal and all but put the game out of reach.